Kyles left her daughter's residence on Southworth Terrace in Kalamazoo, Michigan on September 8, 2007. She said she was going to a friend's house to watch a college football game on television. She was last seen later that day, getting into a black Pontiac Vibe outside her home in the 1200 block of Portage Street. She has never been heard from again. Her relatives reported her missing on September 17. Kyles's Toyota Camry was found abandoned in the 1900 block of Portage Street on September 19, which is her birthday. Her clothes and a suitcase were in the trunk. One window in the vehicle had been broken, but it's unclear whether anything had been stolen. Her disappearance is considered highly suspicious and foul play is possible.